Prof. Dr. Volkan İZOL | Urologist
Prof. Dr. Volkan İZOL | Urologist

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0543 333 33 34

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0543 333 33 34

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Doctor's Office

0322 503 80 70

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0543 333 33 34

Contact

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Botox in Urology

The Use of Botulinum Toxin (Botox) in Urology

Botulinum toxin (Botox) is an effective treatment method used in urology, particularly for conditions such as overactive bladder, neurogenic bladder, and chronic pelvic pain. It reduces urinary incontinence and increases bladder capacity by temporarily paralyzing the bladder muscles (detrusor muscle).

Applications of Botox in Urology
 
A. Overactive Bladder (OAB) and Urge Incontinence
(Urinary incontinence, frequent urination, sudden urge to urinate)
•An overactive bladder is caused by excessive contractions of the detrusor muscle.
•Botox reduces the sudden urge to urinate and urinary incontinence by relaxing the bladder muscles.
•It is an effective option for patients who are resistant to medical treatment.
 
✅ Duration of effect: 6–9 months
✅ It is a repeatable treatment
 
B. Neurogenic Bladder (MS, Parkinson’s, Spinal Cord Injuries)
•Bladder control may be impaired in neurological conditions such as multiple sclerosis (MS), Parkinson’s disease, and spinal cord injuries.
•Urinary incontinence or retention may develop due to excessive contraction of the bladder muscles.
•Botox injections can reduce urinary incontinence by 70–90 percent in patients with a neurogenic bladder.
 
✅ Increases bladder capacity and reduces bladder pressure.
✅ It provides long-term benefits by preserving kidney function.
 
⚠ Disadvantage: Some patients may require the use of a catheter.
 
C. Chronic Pelvic Pain and Interstitial Cystitis
•In interstitial cystitis/painful bladder syndrome, Botox can reduce pain by relaxing the bladder muscles.
•It provides relief by relaxing the muscles in patients with pelvic floor muscle spasms.
 
✅ Prevents excessive contraction of the pelvic floor muscles.
✅ It can lead to a significant reduction in patients' pain scores.
 
Botox Application Method
•The procedure is performed under cystoscopy.
•It can be performed under local, spinal, or general anesthesia.
•100–200 units of Botox are injected into the bladder wall at 20–30 different sites.
•Processing time: 10–15 minutes
 
✅ Hospitalization is not required; patients are usually discharged the same day.
How Long Does the Effect of Botox Last?
•The effects of Botox begin within 3 to 7 days.
•The average duration of effect is between 6 and 9 months.
•The injection can be repeated once the effect wears off.
 
✅ The event continues in recurring instances.
The Benefits and Side Effects of Botox
 
✅ Benefits:
•An effective alternative for patients who cannot take medication or who do not respond to medication.
•It is a minimally invasive procedure that does not require surgery.
•Reduces urinary incontinence and frequent urination.
•It increases bladder capacity and may relieve pelvic pain.
 
⚠ Possible Side Effects:
•Temporary inability to urinate (5–10%, particularly in patients with neurogenic bladder).
•Risk of a urinary tract infection.
•Transient hematuria (blood in the urine).
•Although rare, systemic side effects of Botox (fatigue, muscle weakness).
 
⚠ If the patient is unable to urinate, they may need to use a catheter for several weeks.
Conclusions and Recommendations

✅ It is an effective treatment method for patients with overactive bladder and neurogenic bladder.
✅ Botox injections are a good alternative for patients who do not respond to medication.
✅ The effects last 6–9 months and can be repeated as needed.
⚠ Patients must be carefully selected and monitored due to the risk of urinary retention.

In conclusion:

Botox is a minimally invasive, safe, and effective treatment option in urology. It is an important alternative, particularly for patients who are resistant to medication.

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